Items 1-12 of 99 Results
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High Throughput 3D Cell Culture
High-throughput 3D cell culture is a technology that has great potential, as it allows more accurate simulation of in vivo conditions. One major drawback is the high cost, which can be overcome by automating certain processes. Find out how. -
Development of a High Throughput 3D in vitro Wound Healing Model
Studying wound healing is a challenge, however the ability to quantifying the difference between 3D skin models is now possible. -
Xeno-free MSC culture: high yield, better viability and morphology
Are you trying to mimic in vivo conditions in your MSC cultures as closely as possible, but need to avoid serum? Then find out how the combination of PromoCell DXF medium and a unique coating called myMATRIX help you make your conditions highly physiological while maintaining reproducibility. -
Cells in action: Differentiation of human mesenchymal stem cells into neurons
Cells in action: Differentiation of human mesenchymal stem cells into neurons In this video we can see the differentiation of PromoCell umbilical cord mesenchymal stem cells into neurons. Excitingly, to our knowledge this is one of the first high-resolution, long-term, live cell time-lapses showing this process. These cells were grown for 13 days in PromoCell complete mesenchymal stem cell neurogenic differentiation medium prior to capture of this film. Images were captured every 30 seconds over a 20-hour period using NanoLive’s 3D Cell Explorer. -
Cells in Action: membrane protrusions in HUVECs (Human Umbilical Vein Endothelial Cells)
During angiogenesis, cell-matrix interactions are crucial. The cell matrix structures are involved in migration, invasion and survival of cells throughout the angiogenic process. In this video we can see filopodia and lamellipodia in great detail, thanks to Nanolive imaging's ability to view membrane deformations. These structures are essential for migration, cell-cell interactions, sensing of the cell environment and more. While filopodia appear as long, thin protrusion-like structures that emerge from the cellular membrane, lamellipodia are broad, sheet-shaped structures containing thin and short interconnected actin filaments. -
Cells in Action: Double mitosis of Human Umbilical Vein Endothelial Cells (HUVECs)
Images of cells undergoing mitosis are mind-blowing, and non more beautiful than those of our Human Umbilical Vein Endothelial Cells (HUVECs) captured by Nanolive's 3D Cell Explorer. On the right hand side, the cell seems to enter mitosis but the chromatids don't complete segregation and the cell returns to interphase without dividing. Exiting mitosis is controlled by proteolysis and cyclin dependent kinases (CDKs). Mitosis regulatory machinery sometimes detects errors and forces a return to interphase, as seen here. This kind of research helps develop understanding of the cell cycle, which can be used in myriad applications including cancer research. -
Cells in Action: Mitosis in Human Mesenchymal Stem Cells (MSCs)
Watch the process of cell division in PromoCell's human mesenchymal stem cells! These images were captured using Nanolive’s non-invasive technology, which allows us to access the dynamics of biological processes, such as mitosis, with unprecedented resolution. -
Cells in Action: Human Primary Keratinocytes at the stratum granulosum
Keratinocytes at the stratum granulosum contain two characteristic structures that are visible in this high resolution footage by Nanolive - the lamellar bodies and keratohyalin granules. While keratohyalin granules contain proteins involved in the aggregation of keratin filaments and in the formation of the cell envelope, lamellar bodies contain lipids and fuse with the plasma membrane in order to secrete the content into the extracellular space. -
High-yield isolation of HUVECs in Endothelial Cell Growth Medium 2
Here we show a procedure for a high-yield isolation of primary HUVECs in PromoCell’s Endothelial Cell Growth Medium 2 (ECGM2) and the comparison with a competitor medium. -
Macrophage Cell Culture
Discover PromoCell’s macrophage cell culture portfolio. This ranges from a media system for generating macrophages to assay-ready cryopreserved macrophages, as well as essential macrophage analysis tools. -
Human Cell Culture
Explore our wide range of human primary cells, mesenchymal stem cells, and blood and immune cell types. Find out how our extensive portfolio of cell culture media for a wide variety of human primary cells and cancer cells can help you achieve more accurate, reliable, and reproducible results -
Cancer Cell Culture
Our cancer cell culture portfolio covers a complete range of applications for culturing human malignant cells. Download our brochure to find out more.